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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16616bd16db5c50f2c2a25f778d258ea3e7d46d7c855cd55898cc59620f106cb' 
  AND token = 'o3lpjBxrW/4V0n9aQXpJcXcTHRkBMd3/vJ8Q75THe6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}