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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eec007e02cdbc44f9c4cba0043addb52d7dbb3f576efddfb34d1be4c237c1908' 
  AND token = 'iXk6w+GfvtMmMLqc3lrLI1CRBAMVrlkYUIe37UMqTDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}