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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1c868930b1417e2dd1ab366eacc06da2e3250d86da132b80e4129a4edd8f9e' 
  AND token = 'R6dVvIQ1qqAUAvE7aBlP5EaYrIcI8Kpp1vXWbKayuno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}