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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c4e850560e0d55e2da28ee16f048e7aeebb1ae456cb6e108bdb911b45eb3d6' 
  AND token = 'a7WwgchPaaa4yCQ36xsiYZ9nZgeJz1voE1789GkPBxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}