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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e7bb814285be0cae111e7025aa2319274bcdc2934bf81184051af5ed1ea54c9' 
  AND token = '19+W61GovNWA87KiVGozak7eOPu8F2/YaU7G86LQm5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}