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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11814b2c7de4e0f523131c7141528769a2daca34b084d36d48e6fdd2fffa64c8' 
  AND token = '8pg2TwTLp+BY0Wx795Nj2OCiYD5+2VhpNV1Dbn12NOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}