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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0673133d0fb4c96d201c0bf59a8e1714b0096bbb0a884efb4b5ff07139533352' 
  AND token = 'qOiq0UpDZS/1mPEUKbzb+k0v4hWe4h9JRRbI0CohM90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}