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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4adf527304a90c805d3ebaa2d040da34a1af2610b84059857c73d577b6281fc9' 
  AND token = 'yZgtT+S6y6W6bN+GJhdSrhPVFeRdNDDFwgn7K4A/9wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}