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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46063bb5490903e040c17ee939e1a783bf244e9bcc80e61a9ebef54ddc379e7' 
  AND token = '5o+bPDfECKyw+XD+CfWsqQTZ1rESLLd3RRaZ/FHbU8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}