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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f12bdfd4781d5fadf0881916c0a220c3c29451a226f0821d92dc0cbf7dd606de' 
  AND token = 'QHiCPBlS8aEGMJ0iIojBlraYfT8CNR56f1LJ3NB6Do0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}