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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45664c37b5f8e67ca8063ec936c3d9d370c475b185a81069b1d0db75f0e7d58a' 
  AND token = 'je/BrUVdJJK3e1lCm/4Vqf+aLRBUdCTcROB+JwWn71U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}