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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3bcb516d0d2fe4f2c0c161768c4d4a4132b13bd06cf89b394683193e8ec65e6' 
  AND token = 'o8H8BhzK+3N1+d5Y912HGM3OdRt4OgT2T2WqwCE3Xi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}