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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b04446f8bb79db53f585aec07bb3e9d7d4c63a6c2f34da5bb499d042c3c5c1f' 
  AND token = 'LU1NezHz8RpjbmIyUN8uHxoihXZhxQ5VAgljC6XnDxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}