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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8a4ebe4557181d4cf691eb9fbea35b7fda9800135b1b4f383b41b92dc6a914' 
  AND token = '3Iu/SmLinItCH/6cx2OxqcaoslhD+u1xCLiN5YVMfnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}