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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b75b4aa1f3bb1408ea95d625c9ef924a5e4e54410936e6a1d8ccd85710c25420' 
  AND token = 'E1iN3EKgY8wGQLMKZncoTkVUOv3kfToEcNC4EC6NHAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}