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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4d9d483196338d2604a92b9a3cacc2f647dd7434e52584d3dca0aaa1e88e90' 
  AND token = 'C6dNGGgQi9PG6j7SVx48wENaV0x38AYBwKDORyNTfxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}