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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d9e4b9a53724341521f26ad1e48c2d166011f0fe8dae53df56c609216a0edad' 
  AND token = 'MzkucYiy8g0Nuo4aTxHzp7TughC7/98OFsMN9PjjRaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}