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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3e646bdb862063f569eff65805c8f2a65b9b48f3f7d64a30c68b3d10370b158' 
  AND token = 'RAxcnqN231x1Iriq7XRyf2h82/edloG27Knq6JGQ4OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}