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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0b065da9dcb718bf44b09517f38c69339d1ec9d8283a7f0c4e9b9eeaa2a6340' 
  AND token = 'R7x47FOEEC2O+9XZn71e8BM5OdYJqafgFPOfpm4xI2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}