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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77eb19419282da76db2b5b82c96f58f7a3ced5221b0b728abf71dcd6d4e9bc96' 
  AND token = 'XmLj/qY01+PpJW0DbnM6jguHlg/22/QIoqsoH0fAHQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}