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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53d857358f1ec29e46dec00d37d202ee3381aae62b186732d37ae3498a3c3c3' 
  AND token = 'WTcwa2q5cX0kOmCWJIV/6wXfhwZE+7hesRCDlV/vAmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}