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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48af4ddd06b3c428a7a400a2aaa82a9aaf7a39c7c0521465e9c6e69406a9c3c8' 
  AND token = 'SwjzpuWwoAj4jW4mOtT5B5fUYjJ5hcRXpGBK2VSOHe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}