SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a1dad3e2a14949daa843980b7388792935806477ea8cd2df61d3814c540e43a' 
  AND token = 'O7Bc7k8f45x8I2mCVCRtxhPw7LfRYQJf5lxJr7G/yb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}