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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a8a1dba6acbddc384d12798513deed7398d4e451a0e5b87eedf3b5518f659c' 
  AND token = '0Y8R2qJCr+mO1M4pD83e6KVEe1ELfc7yWu/BVDU1t2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}