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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0de5c302955e4661bbcf81e6e80e6d08c8f46f35123ec8cb6872d0af66fbb9' 
  AND token = 'Wc9Z5kpnRbgvJVA1PptBFDv605IhVRdqgOGJ7jMinJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}