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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5443dec82b7a97749c91a9830d9423dad4d91978f86078e0012cc62d5bee60' 
  AND token = 'pee4om+MS7mG30v9lW6mytOuN51r/1Dp63B+5TW4W80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}