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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1f33009dfa4fa03f0fbba8b906f81f9b5685e8f9ed12ad48132c8b7e209bbf' 
  AND token = '6VOExYTB3m/GTMi5ueACB0K6lVxwNUXjYE+DWX49+Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}