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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5163cc9c84634f28d4c5d0904dd07a988a53f79e00faec4d9dc80c5eecd41852' 
  AND token = 'eWw3Bm9gIlVrh8w2+Rdxft31w2kNpCnMWkW7GEOeGUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}