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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f2c5dd51fa70126df77b59fdd72ef96f3c6de819e017b5a784394061a44ab2' 
  AND token = '+4VmnfkWmVeElYcvO4TDxk4JsP2kMgpgYccp/x9vHkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}