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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503c7e73920df450936531011592e9a79f9cfcdca87a4930d23e23850f45d7cf' 
  AND token = 'BJFkx0/h8+sW3RiwMbZHgK0GNUn2WvLDM7hy91aOyO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}