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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5533c06a14bc0fd50729dd3a4989dfa476456aae3cd92cec78f1d637a06446' 
  AND token = 'g4BTjE/tT3lRT3yz1rtJolowguFz2QtARxuSjfH0nVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}