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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f3f2ab424528db599d2ec2b0a03899b7ef6ff78d6d26bafcb58a306907d7c48' 
  AND token = 'QUVoLZy/o21nCkGjNimUAzBIBv8IFbyfGAdbBIqp8kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}