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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b37c2f437e431b75655f760faa9b5e2392b2857983e462ea6d79779b9ec7445' 
  AND token = 'eQtA1SJ4vKKTSKEafMzVKs0NOsYkfr4LUoLIV79XoWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}