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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc380f40f2211fed8c8d8ed39735b837c858d49b76b61c69acef85c2857509d4' 
  AND token = 'Nwnc20C1ejF6Rrn4LTSk+BxAzrmwsWPZR6WF14wdJbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}