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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb5bee476444481f0c47813840a782960df4ebc36c1b5c63a27c2974f65a07a0' 
  AND token = 'wVgge4R3T6Zjr7RDeS0jJmy6eat5EQQO20/YMxNi2Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}