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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11eb306401960b82a54f4ca6c6641338b5ce249a968f6cfafa7d91df972b4fa1' 
  AND token = 'w9gARvuJT7bpNiuxl0xdMWQHIBWIXdcSyFFJ13XccrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}