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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd351105e5a2aabbb7147024fd154b90091db788189e0aa5c9f49b1c489e1fc79' 
  AND token = 'j2WR2cM+9AHTkejVA0CSxc72sLhadU7YWWlUh4XwuzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}