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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af497677b503890a575c8f420accd2ced354e6ef68ed840d5aa87858bccfba88' 
  AND token = '4g0CiCXrQwFBIi4XP3YI5FRwxFlQTB1T1v+rXjiU9E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}