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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc0b9db81dcad97f563fea427264f52c75f3a12e97d11829e2bd42bb5f30ea4e' 
  AND token = 'fTd55S1W70UEhLHynmC2JdWl9D/6sUcKqxFun5/Cduo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}