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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d7db3c3477ee7690310d0158d60a0a8221268a804aa23c63bb3d018874cf4a2' 
  AND token = '8EU/mWbDjnQhaR1dTyeMQ7/hcowwG19jhiEhp4GIx1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}