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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1741057c41cc59d8049e0e1ee7b10354478b21b80f0c3fda8e3a2d4475b9c644' 
  AND token = '1GRJBpyCROAjDdQChhzHFyi4HvyAbZ5se32UlmPfkO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}