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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595dfe7d90e181a8f5927b395fce9438103638f0c50e5db195ae527f3532773d' 
  AND token = '+duDzvLNIel3hs8tHz7xd4smpGP8jee0IbGjPYfxeWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}