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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd47241987af26a2d1dfab62cfd5a6b0cc8342025620bbe2b5d1d1a9d28684292' 
  AND token = 'f6vQ/x+uF4RveipVkigS3tmkWK+cNjOSjU9SBoqz8Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}