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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866c9d257ab5f4b67a6bee0ada16efb7a4294a3410467fab5eee350f94d438c7' 
  AND token = 't7gVWhO9eCHRuJmOc9UzTLOs5HI0I6jdxgjbUyv29gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}