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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2695e1666e17ed9b655ded7d3eb08368aa1660c47f119e204e26b5413518906' 
  AND token = 'Y1numBvpc45uTdRZkRpW7d0+NZ7bn5kDH9+8RXUIRnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}