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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '012a5da0b60c3dd532d55a726176af012a29d28e923b6735643bd7b73e08c448' 
  AND token = 'KHv+LNER4xpBoh7p+HbUi0v3azkW/cDOLNEKmFjICZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}