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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d60037cb3dd7f922d5dd57d30e967a07ae8e0084636ee24f72fd2e42edf8c4' 
  AND token = 'w3pgkJXV4rwKYGvAFrbCf0c9cLCNSXP7+PBSDIP2LuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}