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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef55740ca20292629e4c74fe8c552ab9d08d874900d712a6dd3bcdc13fc216be' 
  AND token = 'h2WExMlAsKEDYhASk1rfi6z5SwCPn4xLoJXppSq7Q38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}