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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b326b7a5cd9880d25704020bf052a8f30a7447f700baf8c32ddb73f299a41f1e' 
  AND token = 'Nn/dx/xsypHdc2xnaCG5b1gqoBsogM0Sej8BQ8x3iSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}