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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5fadf32bd7d54e8af891e81c868d5191cd817a0d86a22e1b1cdbebe9cb60e5' 
  AND token = '4FfNaSGr0M3IMcCkFQTP01V+tjYVtdw3oVyofacJbM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}